St. Jude study: Statin drugs might fight infections in children with sickle cell

The cholesterol-lowering drugs known as statins are being investigated as a possible treatment for sickle cell disease. Research on mice suggests that the drugs could help lower the risk of bacterial infection in children with the genetic disorder.

A study by researchers at St. Jude Children's Research Hospital in Memphis was published in the Journal of Clinical Investigation. Here are some more details from a PR Newswire release:

In this study, scientists reported that statins prolonged the lives of mice with sickle cell disease following infection with the pneumococcal bacteria. Researchers also reported that a day after being infected, the treated mice had fewer bacteria in their lungs and blood, suggesting statins slowed the spread of the infection.

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